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EU - Priority Endocrine Disruptors

EU Community Strategy for Endocrine Disruptors - Priority List

On December 20, 1999, the (EC) adopted a Communication on a Community Strategy for Endocrine...

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On December 20, 1999, the (EC) adopted a Communication on a Community Strategy for Endocrine Disruptors – a range of substances suspected of interfering with the hormone systems of humans and wild life. The strategy focuses on man-made substances, including chemicals and synthetic hormones, which may harm health and cause cancer, behavioral changes and reproductive abnormalities. Endocrine disruptors have been grouped into the following categories:

  • Category 1: Evidence of endocrine disruption activity (194 chemicals)
  • Category 2: Some evidence of biological activity related to endocrine disruption (125 chemicals)
  • Category 3: No scientific evidence of endocrine disrupting activity 3A: No data available on wildlife relevant and/or mammal relevant endocrine effects (23 chemicals) 3B: Some data available but evidence is insufficient for identification (85 chemicals) 3C: Data available indicating no scientific basis for inclusion in list (0 chemicals-details not provided)

The EC also provides an Access database which contains all of the chemicals reviewed and enables one to separate out the chemicals into the categories identified above. The number of chemicals identified in parenthesis after the category is from this source. Category 3 is not currently included in the Pharos CML

Full report 12/3/2007 at http://register.consilium.europa.eu/pdf/en/07/st16/st16123.en07.pdf

The priority list of chemicals developed within the EU-Strategy for Endocrine Disruptors is no longer updated by EC. The archived report can be found at https://web.archive.org/web/20220307202244/http://ec.europa.eu/environment/chemicals/endocrine/strategy/substances_en.htm.

Hazards for Hazard List
Endpoint Hazard Rating and Description GREENSCREEN® HPD C2C
Endocrine Activity
Endocrine Activity: High to moderate hazard Low confidence
Category 1 - In vivo evidence of Endocrine Disruption Activity Priority List Endocrine Disruption (Red or Yellow)
Endocrine Activity
Endocrine Activity: High to moderate hazard Low confidence
Category 2 - In vitro evidence of biological activity related to Endocrine Disruption Priority List Endocrine Disruption (Red or Yellow)
Endocrine Activity
Endocrine Activity: Low hazard Low confidence
Category 3a (ED Studies available but no indication of ED effects) Endocrine Disruption (Green)
Endocrine Activity
Endocrine Activity: High to low hazard Low confidence
Category 3b (Substances with no or insufficient data gathered) Endocrine Disruption (Red, Yellow, or Green)

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